High Purity 540737-29-9 Tofacitinib citrate rau JAK Pathway Inhibitor

Lus piav qhia luv luv:

Purity:≧99.0%

Txuj Txuj Ci:Enterprise Standard los yog raws li xav tau

Muaj peev xwm:35Kgs / hli

Lub neej txee:Peb xyoos

Daim ntawv thov:Kho rheumatoid mob caj dab, psoriatic mob caj dab, ankylosing spondylitis thiab ulcerative colitis

Pab Pawg Advantage:Kev paub export pab neeg muag khoom nrog kev cob qhia hauv lub hoobkas

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Product Detail

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Khoom cim npe

Khoomnpe	Tofacitinib Citrate
Synonyms	(3R,4R)-1-(Cyanoacetyl)-4-methyl-N-methyl-N-1H-pyrrolo[2,3-d]pyrimidin-4-yl-3-piperidinamine 2-hydroxy-1,2,3 -propanetricarboxylate;CP 690500-10;CP 690550-10;(3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanenitrile 2-Hydroxy-1,2,3-propanetricarboxylate
CAS Nr.	540737-29-9
Qhov tshwm sim	Tawm dawb mus rau dawb hmoov
Molecular Formula	C₁₆H₂₀N₆OC₆H₈O₇
Molecular Luj	504.50 Nws
Daim ntawv thov	Pharmaceutical qib lossis lub hom phiaj tshawb fawb
Ntim	Raws li koj qhov kev thov
Cia	Khaws nyob rau hauv nruj, lub teeb-resistant ntim nyob rau hauv ib qhov chaw txias

Tofacitinib Citrate (CAS #540737-29-9)
Yam khoom	STANDARDS	TSEEM CEEB
Qhov tshwm sim	Tawm dawb mus rau dawb hmoov	Tawm hmoov dawb
Kev txheeb xyuas	HPLC;IR;HNMR	Ua raws
Solubility	Soluble hauv DMSO ntawm 100mg / ml, tsis zoo soluble hauv ethanol, sparingly soluble hauv dej thiab lwm yam.	Ua raws
Poob rau ziab	≤ 0.5%	0.12%
Residue ntawm ignition	≤0.1%	0.05%
Cov hlau hnyav	≤10ppm	Ua raws
Yam khoom muaj feem	Kev kub ntxhov (RS + SR) ≤0.1% Ib qho impurity ≤0.15% Tag nrho impurities ≤1.0%	0.05% 0.14% 0.18%
Enantiomorphism Isomers	≤ 0.2%	Ua raws
Residual Solvents	Ethanol ≤5000ppm Methanol ≤3000ppm Toluene ≤890ppm	Ua raws
Citrate Cov ntsiab lus	36.2% ~ 40%	37.8%
Purity	≥99.0%	99.38%
Assay	60.68% ~ 63.16% ntawm Tofacitinib INN 98% ~ 102% ntawm Tofacitinib Citrate INN	62.04% 99.12%
Xaus: Ua raws

Cov ntaub ntawv tuam txhab

√ Kev tswj cov txheej txheem tag nrho hauv lub Hoobkas thiab cov kws tshaj lij cov neeg ua haujlwm;
√ Zoo yog ib txwm peb xav txog sab saum toj, nruj QC system;
√ 11 xyoo dhau los ntawm pab pawg muag khoom;
√ Kev ywj pheej R & D lab;
√ Ob qhov kev kos npe mus sij hawm ntev GMP kev cob qhia;
√ Cov peev txheej nplua nuj ntawm ntau lub chaw ua haujlwm tsis ua haujlwm rau qhov project customized;
√ Pab neeg ua haujlwm siab ua haujlwm nrog txoj hauv kev zoo ib yam.
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