High Purity USP BP EP 59-05-2 Methotrexate rau Tumor Treatment
Khoomnpe | Methotrexate |
Synonyms | (+) - Amethopterin;(+)-4-Amino-10-methylfolic acid;N-(p-((((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-L-glutamic acid |
CAS Nr. | 59-05-2 ib |
Qhov tshwm sim | Yellow crystalline hmoov |
Molecular Formula | C20H22N8O5 |
Molecular Luj | 454.44 ib |
Daim ntawv thov | Qib tshuaj los yog lub hom phiaj tshawb fawb |
Ntim | Raws li koj qhov kev thov |
Cia | Khaws nyob rau hauv nruj, lub teeb-resistant ntim nyob rau hauv ib qhov chaw txias |
Certificate of Analysis Test raws li: EP9.0 MethotrexateCAS Nr:.59-05-2 ib | ||
Yam khoom | STANDARDS | TSEEM CEEB |
Qhov tshwm sim | Yellow lossis txiv kab ntxwv, crystalline, hygroscopic hmoov | Ua raws |
Kev txheeb xyuas | IR; UV | Ua raws |
Solubility | Xyaum insoluble hauv dej, hauv ethanol (96%) thiab hauv methylene chloride.Nws dissolves nyob rau hauv dilute mineral acids thiab nyob rau hauv dilute daws ntawm alkali hydroxides thiab carbonates. | Ua raws |
Dej | ≤ 13% | 11.8% |
Hais txogTshuaj | Kev tsis haum B≤0.3%impurity C≤0.5%Kev tsis haum xeeb E≤0.3%Qhov tsis zoo H≤0.2%impurity I≤0.2%Unspecified impurities≤0.05% Tag nrho cov impurities uas tsis yog B, C & E≤0.5% | 0.04%0.45%0.03%NDND0.02% 0.04% |
Enantiomeric Purity | ≤ 3.0% | 1.6% |
Hnyav Hlau | ≤ 20ppm | Ua raws |
Sulfated tshauv | ≤0.1% | 0.07% |
Residual Solvents | Ethyl ether ≤ 500ppmAcetone ≤1000ppmEthanol ≤ 2000ppm | 20 ppm63ppm ua48ppm ua |
Assay | 97.0 ~ 102.0% | 99.49% |
Certificate of Analysis Test raws li: USP32 Methotrexate CAS No.: 59-05-2 | ||
Yam khoom | STANDARDS | TSEEM CEEB |
CHARACTERISTIS | Yellow crystalline hmoov | Ua raws |
IDENTIFICATION | IR.UV Conform | Ua raws |
Dej | ≤ 12% | 10.8% |
RESIDUE NTAWM IGNITION | ≤0.1% | 0.07% |
Chromatographic purity | Ib qho impurity: ≤0.5% | 0.27% |
Tag nrho cov impurities: ≤2.0% | 0.73% | |
TSEEM CEEB | Ntawm +19 ° txog +24 ° C | + 21.25 ° C |
QHIA | 98.0 ~ 102.0% | 99.27% |
Cov ntaub ntawv tuam txhab
√ Kev tswj cov txheej txheem tag nrho hauv lub Hoobkas thiab cov kws tshaj lij cov neeg ua haujlwm; √ Zoo yog ib txwm peb xav txog sab saum toj, nruj QC system; √ 11 xyoo dhau los ntawm pab pawg muag khoom; √ Kev ywj pheej R & D lab; √ Ob qhov kev kos npe mus sij hawm ntev GMP kev cob qhia; √ Cov peev txheej nplua nuj ntawm ntau lub chaw ua haujlwm tsis ua haujlwm rau qhov project customized; √ Pab neeg ua haujlwm siab ua haujlwm nrog txoj hauv kev zoo ib yam.Sau koj cov lus ntawm no thiab xa tuaj rau peb